Sisley Paris • Supremya La Nuit Le Grand Soin Sisley At Night Anti-Aging Skin Care Cream Brand New in Box Sample Size .06 oz / 2 ml At the heart of its formula is the brand's Phyto-Complex LC12, a powerful combination of plant-based active ingredients stemmed from Sisley's research on the life of cells. It works at night, which is the key time for cellular regeneration, to repair the cells' past while preparing them for their future. Comfortable like a cream and powerful like a serum, Supremÿa has been designed to be massaged in, which allows the skin to gradually absorb the active ingredients and, within a few weeks of use, has a spectacular rejuvenating effect on your complexion.